Hospital readmissions and poor patient comprehension of discharge instructions remain persistent healthcare challenges, driven in part by low health literacy and ineffective communication. Studies estimate that roughly one-third of Americans struggle to understand basic medical information, and preventable readmissions cost billions of dollars annually. This project investigates which discharge instruction methods (e.g. teach-back, simplified written materials, multimedia tools, or follow-up calls) most effectively increase patient comprehension and if it leads to reduced 30-day readmission rates. My on-site experience will take place at INOVA Alexandria Hospital, a setting offering direct exposure to real interactions during discharge.