Mia C. 2026 | BASIS Independent Brooklyn
- Project Title: Memory Retrieval Through Scent: Assessing Olfactory Cues as a Therapeutic Tool
- BASIS Independent Advisor: Dr. James
- Internship Location: Hunter College, City University of New York (In-Person and Remote)
- Onsite Mentor: Dr. Masayo Omura, PhD
The relationship between olfaction and memory is uniquely powerful due to the direct neurological connection between the olfactory system and the brain structures responsible for emotion and memory, particularly the amygdala and hippocampus. Because odor signals bypass the thalamus and travel directly to these regions, smells can evoke autobiographical memories that are often more vivid, emotional, and rapidly retrieved than those triggered by other sensory cues. This research investigates whether this strong smell–memory connection can be intentionally utilized as a therapeutic tool to support cognitive recall in elderly patients with Alzheimer’s disease. Through a comprehensive review of peer-reviewed literature in neuroscience, psychology, and clinical research, this study will examine how olfactory cues influence autobiographical memory retrieval. Particular attention is given to studies demonstrating that odor-evoked memories in individuals with Alzheimer’s disease are often more specific and retrieved more quickly than memories prompted without sensory cues. By synthesizing these findings alongside current therapeutic approaches such as pharmacological treatments and reminiscence therapies, the research evaluates the potential for structured olfactory stimulation to complement existing interventions. Intentionally pairing familiar or personalized scents with experiences, or reintroducing meaningful odors during therapy, may provide a noninvasive and accessible method for strengthening memory recall, supporting emotional well-being, and helping preserve a patient’s sense of identity. Overall, this research highlights the potential of olfactory cues as an underutilized but promising component of evidence-based therapeutic practices for individuals experiencing cognitive decline.
