
Pragyaa B. 2025 | BASIS Independent Silicon Valley
- Project Title: Dysregulated immune cell infiltration in Idiopathic Pulmonary Fibrosis pathogenesis
- BASIS Independent Advisor: Dr. Allendoerfer
- Internship Location: ilab Research Instiute
- Onsite Mentor: Qian Wang, ILab research institute
This project's goal is to understand the relationship between permanent chronic scarring of the lungs (Idiopathic Pulmonary Fibrosis, IPF) and the immune system. In normal lungs, the scarring of lung tissue is a protective immune response; however, usually there is the regeneration of tissue. In IPF this regeneration is lacking and the scarring initiated from the immune system is uncontrolled. As the lung tissue gets scarred it makes it difficult for the necessary gas exchange to occur.