Pragyaa B. 2025 | BASIS Independent Silicon Valley
- Project Title: Dysregulated immune cell infiltration in Idiopathic Pulmonary Fibrosis pathogenesis
- BASIS Independent Advisor: Dr. Allendoerfer
- Internship Location: ilab Research Instiute
- Onsite Mentor: Qian Wang, ILab research institute
This project's goal is to understand the relationship between permanent chronic scarring of the lungs (Idiopathic Pulmonary Fibrosis, IPF) and the immune system. In normal lungs, the scarring of lung tissue is a protective immune response; however, usually there is the regeneration of tissue. In IPF this regeneration is lacking and the scarring initiated from the immune system is uncontrolled. As the lung tissue gets scarred it makes it difficult for the necessary gas exchange to occur.
My Posts
Week 13 Blog Post
May 10, 2025
Hi everyone! This week, my focus was mainly on writing the paper and working on my presentation. I worked on my introduction, methodology, and results for my paper and my presentation. I am not entirely sure if my filtered DEGs are correct, however, I will run my code again and do some research. For some […]
Read More
Week 12 Blog Post
May 2, 2025
Hi everyone! This week, I was able to finish searching all the genes that I mentioned the previous week. I got quite a few pseudogenes and non-coding genes, but also found some genes that relate to immune cells and different brain cells. I have also started working on my paper by compiling all the research […]
Read More
Week 11 Blog Post
April 25, 2025
Hi everyone, my next few blog posts are going to be focused on the results and paper that I am currently working on. This week, I have been working on a presentation for myself to help understand and analyze my results. I looked at each Gene ontology plot by writing descriptions about each of them […]
Read More
Week 10 Blog Post
April 19, 2025
Hi everyone! Today will be another short post as I am slowly reaching the end of my project and preparing to collect and analyze my results. This week was mostly focused on labeling the graph that compared the IPF clusters with the Normal sample clusters to potentially help draw comparisons between the cell types involved. […]
Read More